2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-methylbutanoic acid
fmoc-D-valine
CAS: 84624-17-9
Molecular Formula: C20H21NO4
2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-methylbutanoic acid - Names and Identifiers
2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-methylbutanoic acid - Physico-chemical Properties
| Molecular Formula | C20H21NO4 |
| Molar Mass | 339.39 |
| Density | 1.229±0.06 g/cm3(Predicted) |
| Melting Point | 143-144°C(lit.) |
| Boling Point | 551.8±33.0 °C(Predicted) |
| Specific Rotation(α) | 17 º (c=1, DMF) |
| Water Solubility | Solubility in methanol (almost transparency). Slightly soluble in water. |
| Solubility | Chloroform (Slightly), DMF (Slightly), DMSO (Slightly), Methanol (Slightly) |
| Appearance | White powder |
| Color | White |
| BRN | 6489548 |
| pKa | 3.90±0.10(Predicted) |
| Storage Condition | 2-8°C |
| MDL | MFCD00062953 |
2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-methylbutanoic acid - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 2924 29 70 |
2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-methylbutanoic acid - Introduction
fmoc-D-valine(fmoc-D-valine) is a chemical reagent mainly used in peptide synthesis and protein engineering in solid phase synthesis. It has the following properties:
1. chemical properties: fmoc-D-valine is a white solid, with hydrophobic. It is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and methylene chloride, but poorly soluble in water. Its molecular formula is C21H23NO5 and its molecular weight is 369.41.
2. use: fmoc-D-valine is one of the important raw materials for the synthesis of peptides and proteins, can be used for the synthesis of biologically active peptides. It is commonly used in solid-phase synthesis to form peptide chains by condensation reactions with other amino acid residues. In addition, it can also be used to study the synthesis of active peptides and drug design.
3. Preparation method: The synthesis of the fmoc-D-valine is usually carried out by a chemical synthesis method. L-valine is first reacted with the Fmoc protecting group to protect the amino group in the chemical reaction. The Fmoc protecting group is then removed by a deprotection reaction to give the fmoc-D-valine.
4. safety information: the fmoc-D-valine has good safety under general conditions of use, but still need to pay attention to the following: avoid contact with skin and eyes, such as accidental contact, should immediately rinse with plenty of water, and seek medical help; During the operation should pay attention to nutrition and personal hygiene; storage should be sealed, avoid direct sunlight and humid environment. When using, please refer to the relevant safety instructions and material safety data sheets (MSDS).
1. chemical properties: fmoc-D-valine is a white solid, with hydrophobic. It is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and methylene chloride, but poorly soluble in water. Its molecular formula is C21H23NO5 and its molecular weight is 369.41.
2. use: fmoc-D-valine is one of the important raw materials for the synthesis of peptides and proteins, can be used for the synthesis of biologically active peptides. It is commonly used in solid-phase synthesis to form peptide chains by condensation reactions with other amino acid residues. In addition, it can also be used to study the synthesis of active peptides and drug design.
3. Preparation method: The synthesis of the fmoc-D-valine is usually carried out by a chemical synthesis method. L-valine is first reacted with the Fmoc protecting group to protect the amino group in the chemical reaction. The Fmoc protecting group is then removed by a deprotection reaction to give the fmoc-D-valine.
4. safety information: the fmoc-D-valine has good safety under general conditions of use, but still need to pay attention to the following: avoid contact with skin and eyes, such as accidental contact, should immediately rinse with plenty of water, and seek medical help; During the operation should pay attention to nutrition and personal hygiene; storage should be sealed, avoid direct sunlight and humid environment. When using, please refer to the relevant safety instructions and material safety data sheets (MSDS).
Last Update：2024-04-09 15:18:00
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Product Name: Fmoc-D-Val-OH Visit Supplier Webpage Request for quotationCAS: 84624-17-9
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QQ: 3008007409
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